Diloxanide Furoate+simethicone+tinidazole
About Diloxanide Furoate+simethicone+tinidazole
Diloxanide Furoate+simethicone+tinidazole is a combination medicine used to treat diarrhoea caused by parasitic infections of the intestines, including amoebiasis (amoebic dysentery) and giardiasis. It also provides relief from excess gas in the gut (digestive tract), bloating, stomach pain, and cramps caused by these conditions. Diarrhoea is a condition in which there is a frequent need to empty the bowels. It is characterised by loose and watery stools.
Diloxanide Furoate+simethicone+tinidazole contains three medications: Diloxanide furoate (an amoebicide), Tinidazole (an antiprotozoal), and Simethicone (an anti-foaming agent). Diloxanide furoate works by killing the parasites in the intestine. Tinidazole damages the DNA of parasites, stopping their growth and reproduction. Simethicone breaks down gas bubbles in the gut, reducing their surface tension and making it easier for gas to be released through flatus or belching (burping). It also helps prevent the accumulation and formation of gas in the digestive tract. Together, Diloxanide Furoate+simethicone+tinidazole helps treat diarrhoea by clearing the infection in the intestines.
You are advised to take Diloxanide Furoate+simethicone+tinidazole for as long as your doctor has prescribed it, based on your medical condition. In some cases, Diloxanide Furoate+simethicone+tinidazole may cause common side effects, such as nausea, vomiting, tiredness, dizziness, headache, loss of appetite, stomach cramps, constipation, and flatulence. Most of these side effects of Diloxanide Furoate+simethicone+tinidazole do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Before taking Diloxanide Furoate+simethicone+tinidazole, inform your doctor if you are allergic to any of its ingredients. Consult your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you are pregnant, planning to become pregnant, or breastfeeding. Let your doctor know if you have a history of diabetes, seizures, a weakened immune system, or liver or kidney disease. Diloxanide Furoate+simethicone+tinidazole may cause dizziness, so avoid driving or operating machines until you are mentally alert. Avoid drinking alcohol while taking Diloxanide Furoate+simethicone+tinidazole, as it may worsen your symptoms.
Uses of Diloxanide Furoate+simethicone+tinidazole
Medicinal Benefits
Diloxanide Furoate+simethicone+tinidazole is a combination medication containing Diloxanide furoate, Tinidazole, and Simethicone. Diloxanide furoate is an amoebicidal medication used to treat amoebiasis. It targets and kills the infection-causing amoeba (parasites) in the intestine. Tinidazole is an antiprotozoal medication used to treat amoebiasis and giardiasis. It is also effective in treating bacterial vaginosis (a vaginal infection) and trichomoniasis (a sexually transmitted infection). It kills parasites and bacteria by damaging their DNA and stopping their growth and reproduction. Simethicone is an anti-foaming agent used to relieve flatulence and bloating. It helps prevent the formation and accumulation of gas in the digestive tract. Together, Diloxanide Furoate+simethicone+tinidazole helps treat diarrhoea by clearing the parasitic infection in the intestine.
Directions for Use
- Diloxanide Furoate+simethicone+tinidazole can be taken with food to prevent stomach upset, or as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Diloxanide Furoate+simethicone+tinidazole as a whole with a glass of water.
- Do not break, crush, or chew it.
- Diloxanide Furoate+simethicone+tinidazole can be taken with food to prevent stomach upset, or as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
- Swallow Diloxanide Furoate+simethicone+tinidazole as a whole with a glass of water.
- Do not break, crush, or chew it.
Storage
Side Effects of Diloxanide Furoate+simethicone+tinidazole
- Nausea
- Vomiting
- Tiredness
- Dizziness
- Headache
- Loss of appetite
- Stomach cramps
- Constipation
- Flatulence
Drug Warnings
Do not take Diloxanide Furoate+simethicone+tinidazole if you are allergic to any of its contents. Let your doctor know if you are taking other prescription/non-prescription drugs, vitamins, or herbal supplements, to rule out any side effects and interactions. You are advised to use Diloxanide Furoate+simethicone+tinidazole with caution if you have diabetes (high blood sugar), phenylketonuria (a genetic condition where the body cannot break down the amino acid phenylalanine), vaginal yeast infections, seizures, a weakened immune system, blood disorders (such as low platelets or anaemia), or liver or kidney disease. Consult your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you are pregnant, planning to become pregnant, or breastfeeding. Diloxanide Furoate+simethicone+tinidazole should be given to children only if prescribed by a doctor. Diloxanide Furoate+simethicone+tinidazole may cause dizziness, so avoid driving or operating machines until you are mentally alert. Avoid drinking alcohol while taking Diloxanide Furoate+simethicone+tinidazole, as it may worsen your symptoms.
Drug Interactions
Drug-Drug Interactions: Diloxanide Furoate+simethicone+tinidazole may interact with certain medications, such as seizure medications (phenytoin), thyroid medications (levothyroxine), immunosuppressant medications (cyclosporine, tacrolimus), blood thinners (warfarin), anticancer drugs (fluorouracil), cholesterol-lowering medications (cholestyramine), and medications used to treat alcohol use disorder (disulfiram).
Drug-Food Interactions: Avoid drinking alcohol while taking Diloxanide Furoate+simethicone+tinidazole, as it may worsen your symptoms.
Drug-Disease Interactions: Inform your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you have certain medical conditions, such as diabetes, phenylketonuria, vaginal yeast infections, seizures, a weakened immune system, blood cell disorders, or liver or kidney disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consuming alcohol while taking Diloxanide Furoate+simethicone+tinidazole, as it may lead to increased dizziness.
Pregnancy
consult your doctorPlease consult your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you are pregnant or planning to become pregnant. Your doctor will prescribe Diloxanide Furoate+simethicone+tinidazole only if the benefits outweigh the risks.
Breast Feeding
consult your doctorPlease consult your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you are breastfeeding. Your doctor will decide whether Diloxanide Furoate+simethicone+tinidazole can be taken by breastfeeding mothers or not.
Driving
unsafeDiloxanide Furoate+simethicone+tinidazole may cause dizziness. Therefore, avoid driving or operating machinery unless you are mentally alert.
Liver
cautionDiloxanide Furoate+simethicone+tinidazole should be used with caution in liver disease. Please inform your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you have liver impairment.
Kidney
cautionDiloxanide Furoate+simethicone+tinidazole should be used with caution in kidney disease. Please inform your doctor before taking Diloxanide Furoate+simethicone+tinidazole if you have kidney impairment.
Children
cautionDiloxanide Furoate+simethicone+tinidazole should be used in children only if prescribed by the doctor.
Habit Forming
Diet & Lifestyle Advise
- Consume bland foods such as bananas, rice, apples, cream of wheat, soda crackers, farina, applesauce, and toast to prevent irritation of the digestive tract.
- Eat fibre-rich food such as whole grains, lentils, beans, broccoli, and peas.
- Avoid eating foods such as milk, dairy products, spicy foods, processed foods, pork, veal, sardines, raw vegetables, rhubarb, onions, corn, citrus fruits, alcohol, pineapples, cherries, seeded berries, grapes, caffeinated and carbonated drinks.
- Drink plenty of fluids or water to stay hydrated.
- Wash your hands thoroughly before eating and also while preparing or serving.
- Wash your hands properly after using the toilet to prevent infections. Clean the toilets regularly with a disinfectant.
Special Advise
- Do not skip doses and finish the prescribed course of Diloxanide Furoate+simethicone+tinidazole, even if you start to feel better. Stopping Diloxanide Furoate+simethicone+tinidazole too early may increase your risk of further infection.
Patients Concern
Disease/Condition Glossary
Diarrhoea: It is a condition in which there is a frequent need to empty the bowels. It is characterised by loose and watery stools. It can be acute (lasts for a few days) or chronic (lasts for at least four weeks). The causes of diarrhoea include food intolerance, food allergy, adverse reaction to medications, viral infections, bacterial infections, intestinal diseases, parasitic infections, and stomach or gallbladder surgery. Common symptoms may include nausea, abdominal pain, cramps, dehydration, bloating, a frequent urge to empty the bowels, and large volumes of loose or watery stools.
Amoebiasis: Also known as amoebic dysentery, it is an intestinal parasitic infection caused by Entamoeba histolytica, which spreads through human faeces. It results in symptoms such as chronic diarrhoea (which may contain blood or mucus), gas, and stomach cramps. In severe cases, it may spread to the liver, causing an abscess (a buildup of pus in the liver).
Giardiasis: It is an intestinal parasitic infection caused by Giardia duodenalis. It spreads through contaminated water and infected foods. It results in symptoms such as diarrhoea, gas, nausea, weight loss, and stomach cramps.
FAQs
Diloxanide Furoate+simethicone+tinidazole is used to treat diarrhoea caused by parasitic infections of the intestines, including amoebiasis and giardiasis. It also helps manage symptoms associated with these conditions, such as excess gas in the gut, bloating, stomach pain, and cramps.
Diloxanide Furoate+simethicone+tinidazole contains three medications: Diloxanide furoate (an amoebicide), Tinidazole (an antiprotozoal), and Simethicone (an anti-foaming agent). Diloxanide furoate works by killing the parasites in the intestine. Tinidazole damages the DNA of parasites, stopping their growth and reproduction. Simethicone breaks down gas bubbles in the gut, reducing their surface tension and making it easier for gas to be released through flatus or belching (burping). It also helps prevent the accumulation and formation of gas in the digestive tract. Together, Diloxanide Furoate+simethicone+tinidazole helps treat diarrhoea by clearing the infection in the intestines.
Do not stop taking Diloxanide Furoate+simethicone+tinidazole even if you feel better, as this may cause the infection to return. To treat your condition effectively, continue taking Diloxanide Furoate+simethicone+tinidazole for as long as your doctor has prescribed it.
Do not take Diloxanide Furoate+simethicone+tinidazole for longer durations unless prescribed by the doctor, as it may cause unwanted side effects. Talk to your doctor if you do not feel better even after taking Diloxanide Furoate+simethicone+tinidazole for a week or the prescribed duration.
Diloxanide Furoate+simethicone+tinidazole might cause a bitter or metallic taste. If you experience any changes in taste, try gargling with water, drinking plenty of fluids, brushing your teeth, or chewing sugar-free mint or gum to reduce the unpleasant taste.
The common side effects of Diloxanide Furoate+simethicone+tinidazole include nausea, vomiting, tiredness, dizziness, headache, loss of appetite, stomach cramps, constipation, and flatulence. Most of these side effects of Diloxanide Furoate+simethicone+tinidazole do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
